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Methamphetamine, also known under the brand name Desoxyn or street names meth, crank, crystal, glass, ice, and speed, is a stimulant drug that speeds up the body’s systems. After marijuana, meth is the second most popular illicit drug in the world, it’s also because of how long does meth stay in your system that makes it popular. it can provide you effects for hours. Methamphetamine is classified as a Schedule II drug in the United States, meaning that it’s considered a drug with a high potential for misuse, with use potentially leading to severe psychological or physical dependence.